One of the biggest challenges in cancer treatment is identifying the chemotherapy regimen that is most likely to work in a particular patient. Caner being a highly heterogeneous disease, chemotherapy response varies widely from patient to patient, even for the same type of cancer. Trial-and-error remains the norm, particularly with chemotherapy, leading to ineffective treatments at high cost and significant avoidable side effects.
Breast cancer is often detected in its early-stages before it has metastasized. These patients require only surgery; however, most receive chemotherapy and/or radiation therapy after surgery unnecessarily. Gab2 test accurately identifies which patient requires chemotherapy or radiation therapy and which doesn’t thereby avoiding the side effects associated with the treatment and unnecessary costs.
According to US FDA, 80% of the chemotherapy drugs are ineffective in a particular patient or are poorly effective. ATP-TCA test will help to identify the drug or combination of drugs most likely to work and avoid drugs that have no chance of working by testing the drugs directly on cells derived from a patient’s tumor. Clinical trial data published in peer-reviewed journal have demonstrated that ATP-TCA test could identify effective chemotherapy drugs
Head and neck cancer is the major group of related cancers. It accounts for 30% of all cancers in India compared with 3-4% in the US. Oral and oropharyngeal cancer (a type of head and neck cancer) cancer can often be treated by surgery alone to achieve complete cure, but current tests do not predict which patients need only surgery and which one needs more aggressive adjuvant chemotherapy or radiation therapy.
OncoR Screening test is a gene-expression test that detects oral cancer in its early stages when it can be fully cured. It is a saliva-based test which makes it very convenient for screening for the disease. The genes were identified using screening studies of patient tumor. The test comprises of monitoring the expression of six genes in disseminated cells in the saliva that are positively and negatively correlated with the incidence of cancer.
Metastasis is the primary cause of death from cancer. Nearly all cancer drugs are designed to inhibit growth of tumor cells or destroy them, while hardly any are directed towards preventing metastasis.
BPL-M7 is a small molecule compound that works through stabilizing the tight-junctions that hold cells together (there is weakening of the Tight-junctions in tumor leading to cancer cells getting disseminated).